New Study Shows Hormone Replacement Therapy (HRT) Cuts Heart Disease 50%. Anybody on HRT? What Does Your Doc Say?

By HeartHawk Latest Reply 2013-03-05 07:04:58 -0600
Started 2012-10-19 23:01:55 -0500

A new large, long-term study showed that HRT in women cut heart disease by a whopping 50%. This would seem to answer the controversy over HRT. But, how many here on on HRT? Perhaps as important, what does your doc say?

Your experience could help many community members.


10 replies

Ted Hutchinson
Ted Hutchinson 2012-12-02 09:09:21 -0600 Report

It's very difficult when researchers quote reductions in relative risk because unless we know what the current risk of an event happening is, it's hard to work out what the reduction in risk really means in terms of lives saved.

If we know that incidence of sudden cardiac death affects 2.4 women per 10,000 then we can work out that a 50% reduction means 1.2 deaths per 10,000 may be saved.

But the downside is the 24% increased risk of Breast cancer from HRT.
We know Breast Cancer incidence is in the region of 12 per 10,000 so a 24% increase results 3 more women suffering Breast Cancer.

PulseToday have an article on this topic.
"Early initiation of HRT 'halves risk of death or CVD'"

There is a useful summary of the issues for and against HRT as a preventative measure for heart disease in this paper.
"How to stay heart healthy in 2011: considerations for the primary prevention of cardiovascular disease in women."
The full text is online here

HeartHawk 2012-12-02 23:26:53 -0600 Report


Ted Hutchinson
Ted Hutchinson 2012-12-03 09:19:50 -0600 Report

I'm not quite sure why the "!"

Surely the aim of every internet health forum must be to enable people to become better informed so they can make better decisions.

It's important that people understand both sides of any debate.

The full text of this study is online.
"Effect of hormone replacement therapy on cardiovascular events in recently postmenopausal women"

But so is the rebuttal.
"Schierbeck et al(1) reported that, after 10 years of an open randomized study, women receiving hormone replacement therapy (HRT) early after menopause had a significantly reduced risk of mortality, heart failure, or myocardial infarction, without any apparent increase in risk of cancer, venous thromboembolism, or stroke. In our opinion, this study results warrant caution.

In this trial, the open label design with a “no treatment” group of comparison creates important risks of bias. The awareness of the treated group about the intervention may affect the behavior of patients and staff in favor of the outcome, reduction of cardiac events. The trial largely took place when HRT was widely believed to reduce cardiovascular events prior to the reporting of the Heart and Estrogen∕ Progestin Replacement Study (HERS).(2) Also, the use of composite outcomes in this trial is problematic. Composite outcomes work often as an exaggerated perception of how well interventions work.(3)

Furthermore, the present study was not designed to evaluate cardiovascular outcomes a priori. The cardiovascular outcomes were not standardized, or monitored by the researchers, but based on individual clinicians’ inclusion of data in a national database."

It really isn't the case that there is only one way to consider this issue.

Coronary heart disease and hormone replacement therapy - from primary and secondary prevention to the window of opportunity.
It's worth reading the abstract.

New WHI analysis links HRT to atrial fibrillation

Lois T
Lois T 2012-11-21 13:32:55 -0600 Report

I hated hearing that my quality of life mattered more than quantity, but that is how we choose for me to go back on HRT after my heart event and stent. I had already had a full hysterectomy, so stopping HRT suddenly was horrible. I've been on HRT again for 8 years, feel great and am not worried either way about my heart health. It's all about exercise and eating right that I can control. Sometimes I think I take too many supplements, not medicaitons, though.

HeartHawk 2012-11-21 21:25:47 -0600 Report


Heh, I am a man but I feel your pain. I'm on thyroid HRT and take a boatload of supplements. Fortunately, you have discovered the health "Big Kahuna!" Diet and ecercise are still the best therapy.


Snicker 2012-11-19 04:34:38 -0600 Report

Hi again I hit the post button before finishing and just want to say men can greatly benifit to by getting their hormones specifically testosterone bioidenticals checked and in balance because heart disease in men can be greater risk for men with inbalances and insufficient testosterone levels. But again Im talking about bioidentical testosterone that our bodies make not synthetic testosterone or not the testosterone body builders use to get bigger muscles. Those can be very dangerous. Bioidentical testosterone is not and can actually help men reduce & overcome heart disease if their levels are out of wack and they get proper HRT treatment by a trained physician in bioidentical horomone therapy who will properly check testosreone levels to evaluate if bioidentical testosterone is needed for the male patient. With women the bioidentical hormones used are estridol or estrial( usually called Biest the best form of boidentical estrogen ) and its made from either soy or yams. Same thing with progesterone for women the bioidentical is made from yam or soy.Hope this helps. Another important thing to take with Bioidenticals is Co q 10 ubiquinol form 100 mg twice a day. And Epa omega 3 also very important to take. I have also found that eliminating all refined carbohydrates and sugars and only eating whole grains in moderation and lots of low sugar fruits and veggies also reduces heart disease risk and improves overall health.

HeartHawk 2012-12-05 23:50:37 -0600 Report


All good stuff. I'd even go as far as to say there are no healthy whole grains especially if thise grains are wheat!


Snicker 2012-11-19 04:09:47 -0600 Report

I take HRT and dr says does help reduce heart disease risk but very important to know the type of HRT to use is only bioidentical hormone replacement therapy which are hormones that are compounded to be identical to the hormones made by our body verses the synthetic hormones in traditional HRT.Bioidentical Hormone Replacement therapy is much safer and is the type of HRT known to reduce heart disease. A good advocate of this type of HRT who has a great deal of knowledge and helped many ladies and even men in this area is the well known actress Susan Somers. I believe her website is but if not just do a search for susan somers bioidentical hormones and you will find many links and much info. Additionally it says here HRT used in women can cut heart disease by 50% and I agree as a user of bioidentical HRT as upon going to dr who practices bioidentical HRT and getting on bioidenticals made by compounding pharmacy my health overall improved significantly including lower cholesterol, normal blood pressure, less fatique, my c reactive pritein which was 3 times above normal went back to normal in 1 month on bioidenticals. Proof they work & synthetic HRT did not is no changes in my health or heart health when tried synthetic HRT & with synthetic developed bleeding

HeartHawk 2012-11-19 20:38:54 -0600 Report


Thanks for the great reply and info!

Yes, my experience is that HRT can be helpful for both men and women but miust be applied on a case to case basis. I was a great candidate for HRT (testosterone) and got expert medical assistance plus had my therapy prepared by a compounding lab. Sadly, it did not work for me (did not lower my Lp(a) but unfortunately did lower my HDL - good cholesterol) but it can work for many others. We are all different. You won't know if you don't try!