Does your statin drug make you feel tired?

HeartHawk
By HeartHawk Latest Reply 2014-07-22 14:05:29 -0500
Started 2012-06-12 14:49:57 -0500

There has been a great deal of speculation that statins cause fatigue. Most docs suggest it is a minor adverse effect but my good friend cardiologist William R. Davis has taken the position that clinically occurs far more often than believed. A new study now adds backup for that belief.

http://www.heartconnect.com/heart-condition-d...

How about you? Do you feel your statin causes fatigue? Let's do in an iformal poll. Reply with what statin you take (Crestor, Lipitor, Zocor, etc.) and to what degree it feel it makes you fatigued with 0=No fatigue and 10=daily and intense fatigue.

The results could help validate how we all feel!

HH


44 replies

RedSun
RedSun 2014-07-22 14:05:29 -0500 Report

I'm taking Lovastatin, 10 mg, every other day. I'm convinced that the "tired" feeling we all have is from the side effects of statins, in that none of us appear to sleep very well. In my case, having to awaken with severe leg cramps to walk off, means my sleep patterns have been drastically altered. As we age, our sleep becomes more important than ever and, when that sleep is altered for any reason, we feel the effects of it. This is the last statin I will ever take, as I've taken all of them and had to stop due to side effects. Lovastatin appears to work better than the others and it is also the oldest and very first of the statin drugs. My cardiologist tells me it also has the shortest life within the body and that may be why I am experiencing less cramping than with other statins; however, the cramps still occur but not on a daily basis. As a point of curiosity, have there been any studies regarding statins and sleep?

tom23
tom23 2014-07-17 12:54:16 -0500 Report

I have been on statins for tree years now I am 49 years old I have 5 stents my weight is 145 ,since they put me on statins I have not been my self always tired sore and just not my self. I also take a bata blocker and a blood thiner I run 3 miles a day.and my number are down tolal cal is 170.can anyone shed some light for me.

rjp66
rjp66 2012-09-07 21:50:29 -0500 Report

I have been taking simvastatin for a couple of years, I have been chronicly fatigued absolutley no energy couldnt sleep so needed ambien just overall felt horrible all the time. About a 2 weks ago i ran out just before a vacation and forgot to pick up by time i returned i felt like a completely new man, energy all day sleep like a baby. I know i need to be on a statin going to see doc next Wednesday just dont know if i want to live feeling that way again! Sure hope there is something out there.

HeartHawk
HeartHawk 2012-09-08 01:02:16 -0500 Report

rjp,

I hear ya! A real "Catch-22!" It's decisions like this we are all faced with. There are many ways to lower cholesterol without statins (diet, exercise, niacin, other drugs, etc.) but when that is not enough some of us must make decision to take a statin. Let us know how it turns out after seeing the doc.

HH

Belfrybats
Belfrybats 2012-07-09 15:41:01 -0500 Report

I've tried every statin drug out there and they all turn me into a pretzel. I decided to try Crestor again and am now back to taking 5 mg every other day. The days that I take it…I feel like I have the flu with muscle aches, body aches and fatigue. So I rate it a 10

HeartHawk
HeartHawk 2012-07-09 23:29:25 -0500 Report

Belfry,

Thanks for chiming in. It is the sharing of vast amounts of info by members liek you that make this community so powerful! Please feel free to post questrions as well on the discussion board.

I just went off Crestor to try the newest statin (Livalo) but will be switching back to 5mg of Crestor as well. I felt worse with Livalo.

One last question, are you taking supplemental CoQ10? If is widely believed that since statins reduce CoQ10 (which is needed by muscle tissue) its depletion is a major contributor to muscle pain. I take 100mg of CoQ10 per day and it helps a lot!

Regards,

HH

Belfrybats
Belfrybats 2012-07-10 07:58:17 -0500 Report

I have not tried CoQ10 but have read about it. I think I will get some at the drug store today. I did try Livalo a few months ago and within four days I could not turn my head. It seems that statins, and some are worse than others, exacerbate the pain and stiffness of the neck and back spurs that I have had for decades. The other muscle soreness I can deal with but if you cannot turn your head to the right or left, you can't do much of anything including driving. I don't even know if Crestor 5 mg every other day is enough to drop the numbers but we will see.

HeartHawk
HeartHawk 2012-07-10 22:19:04 -0500 Report

Belfry,

I found that 5mg of Crestor every day is effective for me but my cardiologist and good friend Dr. William R. Davis, a prominent heart disease and prevention and reversal expert, suggests 5mg every other day can be effective for some.

HH

harley64
harley64 2012-07-07 15:47:53 -0500 Report

I'm taking Crestor and I feel tird all the time as well. I rate it at about an 8

HeartHawk
HeartHawk 2012-07-08 00:29:00 -0500 Report

harley,

I recently switched from Crestor (5mg) to Livalo (1mg) but can't say I noticed a difference. Of course, I stopped taling 100mg of CoQ10 so that may be the problem. I willstart taking taking it again next week to see if that helps. I helped a little with Crestor.

HH

harley64
harley64 2012-12-13 21:47:57 -0600 Report

I was on the simvastatin before and was replaced with Lipitor, I was briefly on Zetia then to Crestor. They all make me feel tired. I have no energy, I have even tried taking Vitamins to help give me energy

harley64
harley64 2012-12-16 10:25:12 -0600 Report

No I am not takin CoQ10. What is that and is it only by prescription? Is this something I should talk to my doctor about? Just wondering.

HeartHawk
HeartHawk 2012-12-16 22:16:18 -0600 Report

harley,

No, CoQ10 is a natural supplement available at any health store. CoQ10 is needed by muscles but statins are known to decrease your body's natural CoQ10. That is why many statin users take this supplement.

HH

re1ndeer
re1ndeer 2012-06-14 19:06:39 -0500 Report

I take simvastatin (zocor) 40mg, yes I feel it makes me fatiqued. I t seems I'm tired all the time. I rate it a 10.

HeartHawk
HeartHawk 2012-06-14 22:52:24 -0500 Report

re1ndeer,

Yeah, I hear it all the time. 10 is nasty. Two questions.

  1. Are you taking Co-Q10, if so, how much? Co-Q10 is supressed by statins which is needed by the muscles.

  2. Have you tried other statins? Simvastatin is pretty old and is eliminated via the CYP34A pathway. Have you tried other statins? For example, Crestor (rosuvastatin) is more powerful which means a smaller dose. It is also eliminated via the CYP2C9 and CYP2C19 pathways which are less competitive and may be more efficient for your metabolism.

Let us know!

HH

re1ndeer
re1ndeer 2012-06-15 07:51:12 -0500 Report

I originally was on Crestor, many years ago. Insurance would not cover it anymore (at that time - no generic), so I was put on simvistatin.
I've heard about Co-Q10, did not know what it was, still really don't. Never was on it.

HeartHawk
HeartHawk 2012-06-16 02:04:13 -0500 Report

re1ndeer,

CoQ10 is needed by muscles to function and it has definitively been shown to be supressed (along with cholesterol production) by statins. CoQ10 is sold as a natural supplement and has been clinically shown to relieve statin induced muscle pain in many. I am surprised your doc has not mentioned this. Ask about it!

http://www.heartconnect.com/heart-condition-articles/29-using-supplements-to-fight-statin-side-effects?category=complications

Also, note that Lipitor just went off patent and will be available in generic (cheaper) form.

http://www.heartconnect.com/news-articles/463-lipitor-goes-generic-what-it-means-for-you/portal

HH

re1ndeer
re1ndeer 2012-06-19 16:46:27 -0500 Report

Saw the doctor today, wants me to stay on the simvastatin (as it is working), but, He told me to TRY the Co Q-10, for one month, if no improvement, then to stop. So, as of today I will be taking 1 softgel of 200mg per day.

HeartHawk
HeartHawk 2012-06-20 00:04:34 -0500 Report

re1ndeer,

That should be plenty to get any potential benefit. Since we are all different there is no guarantee but it does work for me!

HH

re1ndeer
re1ndeer 2012-06-22 14:22:45 -0500 Report

I had to drop the 200mg softgel of Co-Q-10, had too many side effects, doctor dropped me to 50mg per day, will let you know how well it works.

re1ndeer
re1ndeer 2012-06-22 22:55:41 -0500 Report

I had both dizzieness and stomach cramps. I know there are a few more, but, these really did me in.

HeartHawk
HeartHawk 2012-06-23 22:28:02 -0500 Report

re1ndeer,

I checked into CoQ10 side effects and sure enough dizziness and nausea/upper abdominal pain were on the list along with insomnia (#1), rashes, , sensitivity to light, irritability, headache, heartburn, and (surprisingly) fatigue.

Once again, it proves we are all different and what helps one person might cause problems for another!

HH

Judy560
Judy560 2012-06-23 18:54:53 -0500 Report

Everyone is different and there are side effects from Simvastatin. So did your doctor give you a new cholestrol medication?

re1ndeer
re1ndeer 2012-06-23 18:58:07 -0500 Report

No, the simvastatin is working fine, only really fatigued, been on this drug for over 5 years. The problem was with the Co-Q-10 with the stomach cramps and dizziness.

Judy560
Judy560 2012-06-19 21:57:31 -0500 Report

My simvastatin doesn't make me sleepy maybe your not taking them correctly. You take your statin either after your last meal or right before bed. I take vitamin b12 to boost my energy level and I get more done in a day. I checked with my doctor at VA and were trying to get my cholestrol down so they took some blood today. Get the results in a couple days. There thinking of switching me to crestor but they need the results first. I'll keep you all posted.

HeartHawk
HeartHawk 2012-06-20 00:06:00 -0500 Report

Judy,

Please do. I have been using Crestor for years and am thinking of switching to Livalo just to give it a try.

HH

deadpidgeon
deadpidgeon 2012-06-21 19:57:35 -0500 Report

It doesn't seem very intelligent to change meds 'just to give it a try'. A real doctor will tell you not to change what works.

HeartHawk
HeartHawk 2012-06-22 00:44:25 -0500 Report

pidgeon,

In many cases I would agree but I now take CoQ10 to to ward of the side-effects of Crestor. Livalo is eliminated via a different pathway and is more powerful which means I may be able lower the dose. It holds the promise of eliminating my muscle aches so I do not need the CoQ10 (which is also expensive). I have a combination that works but is not optimum.

HH

deadpidgeon
deadpidgeon 2012-06-22 00:59:35 -0500 Report

Yea, that coenzyme is expensive. I think it helped me. My heart function was down to 25%. Over a couple years I got it back up to over 55% which I am told is about average for my age. Of course, the digoxin helped too.

Judy560
Judy560 2012-06-20 14:43:30 -0500 Report

They want to wait for the blood results before they change it to Crestor or Livalo. The doctor said either one once he gets the results.

HeartHawk
HeartHawk 2012-06-17 00:50:35 -0500 Report

CW,

Both you and re1ndeer take simvastatin and have a similar problem. Are you taking the same dose (40mg) as re1ndeer?

HH

Judy560
Judy560 2012-06-17 14:45:40 -0500 Report

Thanks for the tip ! Going to look into taking Co-Q10. Was wondering why my muscles were hurting. Although I'm not allowed to lift anything heavier then 10 pounds so I made my daughters help my husband with the recent move. Still going through the boxes and trying to get organized. But the Simvastatin doesn't make me tired it helps my cholesterol levels pretty good.
I'll talk to my doctor about crestor though.

CWMecca
CWMecca 2012-06-14 11:32:15 -0500 Report

I'm not sure what statins I'm on but I know I'm on at least one. I have to nap every single day, anywhere from 2-4 hours because I'm so tired and I'm not all that active! It's annoying and I don't get as much done as I'd like. So I'd rate it at 10.

HeartHawk
HeartHawk 2012-06-14 22:54:22 -0500 Report

CW,

That is two 10s in two replies (see re1ndeer's reply). Check your prescription bottle and let us know exactly which statin you may be on so we can keep track.

HH